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Author Topic: Epinephrine Nasal Spray in Phase 1 of Trial  (Read 156 times)

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Offline Macabre

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Epinephrine Nasal Spray in Phase 1 of Trial
« on: December 11, 2017, 01:23:53 PM »
https://snacksafely.com/2017/12/phase-i-trial-of-epinephrine-nasal-spray-for-anaphylaxis-begins/

Quote
INSYS Therapeutics announced Thursday that it has begun a proof-of-concept study of two formulations of epinephrine nasal spray for the treatment of anaphylaxis with the enrollment of the first patient.

This Phase I clinical trial is designed to establish whether intranasal administration of epinephrine is bioequivalent to the standard method of delivering the drug via intramuscular injection. . . . .


Me: Sesame, shellfish, chamomile, sage
DS: Peanuts

Offline PurpleCat

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Re: Epinephrine Nasal Spray in Phase 1 of Trial
« Reply #1 on: December 11, 2017, 04:54:03 PM »
Exciting!

Online spacecanada

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Re: Epinephrine Nasal Spray in Phase 1 of Trial
« Reply #2 on: December 11, 2017, 05:25:08 PM »
I have to wonder how well a nasal spray would work with nasal symptoms being part of a reaction.  Think of a really snotty reaction; I don't think a spray could be effective then, or when you have congestion from other conditions such as viruses.  It will be interesting to see how the trial considers those factors. (They are spraying allergens in the nose and seeing how it affects the epinephrine.)

Sounds like an interesting experiment, for sure. 
« Last Edit: December 11, 2017, 05:32:17 PM by spacecanada »
anaphylaxis to tree nuts, peanuts, and potatoes; severe dairy intolerance; vegan (preference)
family members allergic to dairy, egg, peanut, sesame, shellfish