From the American College of Allergy, Asthma and Immunology meeting

[Macabre]

I will post tweets I see coming out the current meeting of the American College of Allergy, Asthma and Immunology.


 @allergistmommy: RT @IgECPD4: Significant reduction in milk allergy if continually fed baked milk. 76-80% outgrew vs comparison: 24-33%#ACAAI

@allergistmommy: RT @ACAAI: Statin Alert: A new study shows taking statins for high cholesterol may worsen #asthma. #ACAAI

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@isitallergy 
Introducing:First and Only FDA-cleared allergen component tests for peanut #ACAAI meeting. Visit us booth 1024. http://bit.ly/tbtZMV

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@AllergieVoeding: Follow the #ACAAI hashtag to obtain information about the meeting of the American College of Allergy in Boston, November 4-7

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 @IgECPD4 Flu vaccine assoc with mild hives (4%) even in severe cases. Mild egg allergy FP office. Severe allergist office--AAP guideline#ACAAI

 @IgECPD4 1 parent with food allergy doubles risk of food allergy in kids. 2 parents triples risk-Finnish data#ACAAI

@IgECPD4  Camel's milk lacks beta-lactoglobulin, but 20% CMA still allergic. Prick test to camel milk helpful#ACAAI

@IgECPD4 Camel milk can still cause anaphylaxis#ACAAI

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 @IgECPD4 90% of Italian patients on SLIT stopped before reaching the 3 year mark#ACAAI

@IgECPD4 SLIT patients receiving followup 4 visits/yr 82% adherence. 1 visit/yr: 30% adherence#ACAAI

[Macabre]

@IgECPD4 Baked milk tolerant children:60% tolerated unheated milk over 5 yr period. 28 x more likely to become tolerant to milk#ACAAI

@IgECPD4 Significant reduction in milk allergy if continually fed baked milk. 76-80% outgrew vs comparison: 24-33%#ACAAI

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@IgECPD4  Best individual marker for peanut allergy is IgE to r Ara h2. Ara h6 increases specificity#ACAAI

@IgECPD4  Peanut OIT study. 10% got epi during escalation in hospital but 84% completed 1 yr. Desensitized group: 5 g. Placebo: 280 mg#ACAAI

@IgECPD4  Of 88 children with delayed MP/urticarial rash only 6.8% reacted to re-challenge. Pen allergy over-diagnosed#ACAAI



@IgECPD4  Basophil activation test--RCM added to basophils showed positive result in 50% of pts with documented reactions. Not ready#ACAAI

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@IgECPD4 Short intervals between stings are a risk factor for anaphylaxis. Blum Allergy 2011#ACAAI

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@IgECPD4  Diversity of bacteria in farm homes may be the protective factor against atopy#ACAAI

@IgECPD4
David Fischer Hayfever data didi not show much difference between 1955 and 1995 from Hal Nelson's data but asthma has a much bigger increase

@IgECPD4
David Fischer Even in Africa where the asthma rates are low there is an urban affluence link to high positive DM titres#ACAAI

@IgECPD4
David Fischer In Costa Rica there is a similar pattern where the water is cleaner, shoes are common and helminths eradicated but more asthma#ACAAI

@IgECPD4
David Fischer Teens who had cats in the 1st year of life had a decreased risk of cat allergy at the age of 18.#ACAAI

@IgECPD4
David Fischer Dog exposures more protective re: all forms of allergy not just dogs. Perhaps the same as barnyard protection#ACAAI


@IgECPD4
David Fischer Platts Mills reviewing data on frequent washing esp with soap harming the skin barrier which may lead to increased sensitization#ACAAI

@IgECPD4
David Fischer Alpha-gal exposure in Africa leads to high positive cat titres but no increased asthma rates#ACAAI

@IgECPD4
David Fischer NHANES data shows 2-5X increase in atopy from the 80's to the 90's#ACAAI

@IgECPD4
David Fischer Inverse correlation between parasite exposure and atopic responses most recently suggested in East Germany#ACAAI


In Venezuela children treated for worms noted to have increased atopic rates improves with re-infection#ACAAI

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@IgECPD4
David Fischer Possible links to lack of Omega 3 as risk factor for atopy (epidemiology).Supplementation studies in active disease disappointing#ACAAI

@IgECPD4
David Fischer Meta-analysis of various trials with varying protocol designs showed no help but methods of administration differed#ACAAI

@IgECPD4
David Fischer 9% of American deficient in Vit D and 61 % insufficient. 28% in Costa Rica as well#ACAAI

@IgECPD4
David Fischer Multiple small studies link lower serum 25(OH)D3 levels and various markers of asthma incl assoc with FEV1#ACAAI


@IgECPD4
David Fischer No long-term studies with Vit D. Dose to aim for unknown #ACAAI

@IgECPD4
David Fischer Int Arch Allerg study showed odds ratio 4.2 for increased asthma risk ePUB with Vit D deficiency #ACAAI

@IgECPD4
David Fischer Other studies not as supportive of Vit D and some show worsening. Could be Vit D and genetic factors #ACAAI

@IgECPD4
David Fischer Need multiple level measurements of Vit D (OH)3 over the course of the year and prove the reaching of Vit D sufficiency in trials #ACAAI

[GoingNuts]

Keep 'em coming, McC - very interesting stuff!

[CMdeux]

I agree-- AWESOME stuff!!   

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@AllergicVegan Melanie Carver
At #ACAAI meeting? Visit Kids With Food Allergies Foundation @kfatweets to find out more about how we support your food-allergic patients.

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@ACAAI Improvement needed: Study shows treatment guidelines not followed after food-induced anaphylaxis. #ACAAI

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@wheezemd
Michael Blaiss, MD 'Food Challenges' Provide Best Allergy Diagnoses: Study at #ACAAI http://bit.ly/vfyQ4J