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Author Topic: Non IgE mediated egg allergy  (Read 728 times)

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Offline LinksEtc

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Non IgE mediated egg allergy
« on: August 26, 2014, 07:32:14 PM »
Ever since dd was very young, she could not tolerate too much egg white without getting stomach issues.  We've never been too formal about it all ... we always just tried to avoid giving her amounts that would cause her problems ... I've never really known what to call this issue.

She had some bloody "D" as a toddler (could tolerate no egg or milk for a few weeks), but that had not happened again until this summer.  The GI & I decided to purposely add more egg white to her diet for a month before scopes to check for EGID ... increased tummy aches, D, & eventually bloody D again followed.  After the procedures, the GI told me that she thinks dd has an egg FA.

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Later this summer, we had an appointment with Dr-FA-Yoda  :) .  She thinks that it's likely that dd has a non IgE mediated egg allergy.  My understanding is that there are different medical approaches to dealing with this.  Some docs think that the food should be completely avoided because even if no symptoms, there still could potentially be some damaging inflammation going on.  We've decided to take the other approach and allow the forms of egg that she tolerates .... dd is so used to eating foods with some egg in them that I think it would be really hard for her to change now.

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So here are some links ....


"Food Allergy"
http://www.worldallergy.org/professional/allergic_diseases_center/foodallergy/
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Allergic eosinophilic oesophagitis, gastritis or gastroenteritis: The exact cause of these disorders remains unknown although both IgE-mediated and T-cell-mediated reactions have been implicated.

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Dietary protein enterocolitis syndrome

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Dietary protein proctitis

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Dietary protein enteropathy



"Non-IgE mediated food allergy."
http://www.ncbi.nlm.nih.gov/pubmed/18782024
Quote
The immune-mediated adverse reaction to food is defined as food allergy (FA) which is roughly divided into IgE mediated or non-IgE mediated FA (NFA). As opposed to IgE mediated FA, NFA primarily affects the GI mucosa. In addition, there is far less of an understanding of NFA than IgE-mediated FA and its clinical relevance is likely under-estimated in most cases.



"Mechanisms of IgE-mediated allergy & Non-IgE-mediated immune reactions"
http://www.medscape.com/viewarticle/721702_2


"FPIES: Food Protein Induced Enterocolitis Syndrome"
http://www.kidswithfoodallergies.org/resourcespre.php?id=99

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I didn't ask either doc yet which sub-category of non-IgE might be the most likely ... it wouldn't surprise me if all categories aren't even known yet.  Most likely it won't make much of a difference in how we manage it.  A lot of the descriptions don't fit dd great as many often affect infants or involve vomiting (which dd doesn't get).


So a big shrug.  Just sharing it here in case it is helpful to anybody & because it seems a bit unusual. 

If I learn anything else interesting, I'll let you know.






« Last Edit: August 26, 2014, 07:37:34 PM by LinksEtc »