CITYPASS-- seriously-- the cable-car rides alone will make it pay for itself. Streetcar, bus, etc.
Take the cable car up and down Russian Hill from Ghiradelli sq. at night. LOVELY.
AND that pass gets you into MoMA, CAAS, Exploratorium, Aquarium, Alcatraz,
and-- the thing that I
cannot recommend enough-- the Asian Museum of Art.
BEST museum I've ever been in. (And I've been to several in Paris and London-- The Louvre was pretty cool too, LOL).
Yup.
CityPass.Also-- be aware that some Safeways now have grind-it-yourself stations near produce areas. Just a head's up on that one.