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Discussion Boards > Allergy Research & News
New Hope for curing food allergies article
socks on a rooster:
http://www.msnbc.msn.com/id/44858044/ns/local_news-chicago_il/#.TpRVMXJgjCM
rebekahc:
It's worth keeping this on the radar, but this statement makes me wonder.
--- Quote ---Previously, the approach was used to target autoimmune diseases like Type 1 diabetes and multiple sclerosis.
--- End quote ---
AFAIK, those diseases haven't been cured. If they've tried this technique on those and it works, why aren't they treating with it? If it didn't work on those, I wonder what the chances are of it working with allergies?
Ra3chel:
Bit more here: http://io9.com/5848745/
CMdeux:
The original citation is:
http://www.jimmunol.org/content/early/2011/10/04/jimmunol.1100608.abstract
I (personally) find this interesting:
Interestingly, Ag-SP induced Th2 tolerance was found to be partially dependent on the function of CD25+ regulatory T cells in the food allergy model, but was regulatory T cell independent in the model of allergic airway inflammation.
In other words, something that wasn't supposed to be a variable turned out to be highly correlated to the success of the response. Meh. I'm skeptical, because that often means that the underlying (supposed) mechanism isn't correct-- or at the very least, is incompletely understood.
In some conditions, in some animal models, this works. As long as nothing interferes.
Susan:
What about this?
--- Quote ---Researchers from the University of Notre Dame have announced a breakthrough approach to allergy treatment that inhibits food allergies, drug allergies and asthmatic reactions without suppressing a sufferer’s entire immunological system.
The therapy centers on a special molecule the researchers designed, a heterobivalent ligand (HBL), which when introduced into a person’s bloodstream can, in essence, out-compete allergens like egg or peanut proteins in their race to attach to mast cells, a type of white blood cell that is the source of type-I hypersensitivity (that is, allergy).
--- End quote ---
http://newsinfo.nd.edu/news/26774-researchers-engineer-new-way-to-inhibit-allergic-reactions-without-side-effects/
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