Posted by: StridAst
« on: December 22, 2017, 04:06:52 PM »Agreed on nausea and cramps without other symptoms not being typical of food allergies. It is *very* typical for chronic stomach things with mast cell disorders. Though even then one would expect other symptoms, they just wouldn't necessarily be obviously connected. Like the skin hypersensitivity and anxiety *could* both count as other symptoms with mast cell disorders. In classic allergies, the IgE antibodies trigger the mast cells, which release a ton of different chemicals, which cause the symptoms, the symptoms are usually varied, and with increased severity usually comes an increase in the number of symptoms. With mast cell disorders, the mast cells themselves are not functioning correctly, so things change. You can get release of those chemicals without the IgE triggers, you also tend to get fewer chemicals released, or different chemicals released for different stimulous. This leads often to single symptoms that seem disconnected from the other symptoms.
Of course other things can cause the GI issues, the skin stuff, and the anxiety. Hence my question about other reactions Since with mast cell disorders you expect both chronic *and* acute symptoms. Multiple vitamin deficiencies goes hand in hand with anything wrong with the digestive tract, and anxiety can easily be caused by deficiencies (especially hormone deficiencies like vitamin D which is, in fact, a hormone) so there are multiple possible causes, but none of those tend to cause the skin hypersensitivity (assuming it's a type of dermatographia).
Edited to add a couple things
Of course other things can cause the GI issues, the skin stuff, and the anxiety. Hence my question about other reactions Since with mast cell disorders you expect both chronic *and* acute symptoms. Multiple vitamin deficiencies goes hand in hand with anything wrong with the digestive tract, and anxiety can easily be caused by deficiencies (especially hormone deficiencies like vitamin D which is, in fact, a hormone) so there are multiple possible causes, but none of those tend to cause the skin hypersensitivity (assuming it's a type of dermatographia).
Edited to add a couple things