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Discussion Boards => Main Discussion Board => Topic started by: eragon on October 19, 2013, 07:36:11 AM

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Title: request for new epi pens
Post by: eragon on October 19, 2013, 07:36:11 AM
http://www.emerade.com/hcp/adrenaline-auto-injector
Title: Re: request for new epi pens
Post by: twinturbo on October 19, 2013, 09:56:47 AM
That is both sobering and intriguing.

My husband's on schedule to attend an allergy conference next month in Asia with some presenters from Germany. I'll see if he can finesse a trainer somehow.
Title: Re: request for new epi pens
Post by: CMdeux on October 19, 2013, 12:27:23 PM


Quote
There is no upper temperature restriction.


WOW.


That looks like a GREAT device, Eragon.  I'm openly envious, now.
Title: Re: request for new epi pens
Post by: twinturbo on October 19, 2013, 12:51:12 PM
^Any ideas on how they achieved greater stability? The literature states the shelf life is longer as well.
Title: Re: request for new epi pens
Post by: CMdeux on October 19, 2013, 01:25:39 PM
uv protection would be one guess.

The others are:

a) possible extended dosing evaluation-- recall, Dey/Mylan doesn't exactly have a profit motive for testing efficacy/degradation out past expiry.  My guess is that they haven't.  There's just not much literature on the subject either way-- and yet people routinely store them in high heat and then report some efficacy even with devices which are YEARS out of date, so...

b) proprietary buffering with redox scavengers-- but this one is something of a long shot, IMO.  They might degass buffering solutions with nitrogen or even with a noble gas, though-- and that might really make a HUGE difference when coupled with excellent UV protection.


Title: Re: request for new epi pens
Post by: Macabre on October 19, 2013, 02:25:57 PM
Wow. That is so cool. Longer needle meets many of the concerns about injecting into overweight persons.  And it's slimmer! I love it.
Title: Re: request for new epi pens
Post by: twinturbo on October 19, 2013, 02:50:55 PM
I noticed in one chart a comparison was made between Emerade, EpiPen and Jext. I couldn't find much about Jext other than their main presence but it looks like it shares form factor with an EpiPen.