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Topic Summary

Posted by: spacecanada
« on: April 07, 2022, 07:56:11 PM »

Very exciting news!
Posted by: GoingNuts
« on: March 30, 2022, 12:06:02 PM »

This could be HUGE!
Posted by: Macabre
« on: March 30, 2022, 11:45:09 AM »


Researchers Discover Key Source of Allergies and Anaphylaxis

Which brings us back to the POSTECH discovery, the study for which was recently published in the journal Nature Communications. The research team verified for the first time that plasma B cells secreting IgE were present in the thymus of mice models. The thymus is a lymphatic gland located in the upper chest beneath the breastbone in humans.

They found the thymus-derived IgE promotes food-induced anaphylactic reactions by increasing the number of mast cells in the intestine. This study is the first to identify the origin and development of the IgE and mast cells that cause allergic disorders.

The findings are significant in that they identify the origin of the thymus-derived IgE and its role in allergic disorders which will help toward meaningful advances in the study of therapeutics for allergic disorders and anaphylaxis in the future.