Well, it
sounds as though that could be the same thing that cromolyn has done... well,
pretty much forever. It's a mast cell stabilizer.
At least it's the same idea.
Problems with that particular approach:
- must demonstrate TRUE inertness and perfect pharmacological targeting if you plan to use a foreign molecule as a life-long treatment for a chronic condition
- most of these types of molecules have high 'off' rates-- that is, you need to redose VERY frequently, because they come off of the binding site pretty readily as soon as blood concentrations dip.
The real solution is probably targeted gene therapy which directs a patient's own body to MAKE the interfering ligand at a pretty significant rate. But there are (currently, anyway)
huge problems with using gene therapy this way, even in the very simplest models. Expression levels just aren't very predictable.